- Madrid – The capital of Spain, known for its art museums like the Prado and Reina Sofia, as well as its vibrant nightlife.
- Barcelona – The cosmopolitan capital of Catalonia, famous for its architecture, including works by Antoni Gaudi.
- Seville – The capital of Andalusia, known for its historic sites like the Alcazar and Giralda Tower, as well as its lively flamenco scene.
- Granada – Known for the Alhambra, a UNESCO World Heritage Site and one of the most visited tourist destinations in Spain.
- Valencia – Known for its futuristic City of Arts and Sciences complex and the traditional Las Fallas festival.
- Toledo – A medieval city with a well-preserved old town, known for its religious and cultural heritage.
- Santiago de Compostela – The final destination of the Camino de Santiago pilgrimage, known for its cathedral and historic city center.
- Bilbao – Known for the Guggenheim Museum Bilbao, as well as its lively food and drink scene.
- San Sebastián – A coastal city known for its beaches and delicious Basque cuisine.
- Ronda – A mountain town known for its dramatic gorge and historic bullfighting ring.
- Córdoba – Known for its historic center, including the Mezquita, a mosque turned cathedral.
- Segovia – Known for its well-preserved Roman aqueduct and medieval castle.
- Cuenca – A hilltop town known for its well-preserved medieval architecture and views.
- Avila – Known for its well-preserved medieval walls and historic churches.
- León – Known for its Gothic cathedral and well-preserved medieval architecture.
- Salamanca – Known for its historic university and well-preserved old town.
- Burgos – Known for its Gothic cathedral and historic city center.
- Girona – Known for its well-preserved old town and Jewish quarter.
- Vitoria-Gasteiz – Known for its historic old town and green spaces.
- Palma de Mallorca – Known for its historic old town, beaches, and nightlife.